Summary
w88 slot Interests
My research program strives to improve mass spectrometric-based detection and analysis of biomolecules. In particular, we pair mass spectrometry with chemical derivatization, photon irradiation, ion mobility, and radical w88 slot to elucidate the three-dimensional structure of proteins, better characterize the acidic and hydrophobic proteome, detect and localize post-translational modifications. Centered at the interface of w88 slot and biology, my research program provides students with the opportunity to tackle both biochemically-focused projects and biophysical questions at the core of the techniques themselves. Currently, my group is recruiting students for three projects:
1) Equipping a carbon monoxide laser to a w88 slot spectrometer, characterizing the behavior of irradiated biomolecules, and applying infrared multiphoton dissociation (IRMPD) to instruments and at pressure regimes traditionally precluded from this technique.
2) Probing protein w88 slot with photocaged small molecule reagents both in vitro and in vivo and demonstrating the utility of the temporal and spatial control that is provided by these probes.
3) Applying the tandem w88 slot technique free-radical initiated peptide sequencing (FRIPS) to complex mixtures of anions.
Publications
Please see w88 slotGoogle w88 slot pagew88 slot latest list of publications.
Education
- Postdoctoral Scholar (2016-2019), w88 slot Michigan (K. Håkansson and B. R. Martin)
- Ph.D., w88 slot (2016) University of Massachusetts (R. W. Vachet)
- B.S., Biochemistry (2007), Northeastern w88 slot