Summary
Anthony W. Czarnik was born in Appleton, Wisconsin on November 21, 1957. He attended public schools in Appleton, Combined Locks, and Kimberly, Wisconsin, and received his B.S. (cum laude) from the University of Wisconsin-Madison in 1977. His undergraduate major was biochemistry, but he carried out undergraduate research during that time in two organic laboratories: at UW-Madison (with Prof. Vedejs) and at Argonne National Laboratory (with M. MacCoss). Dr. Czarnik received his graduate training at the University of Illinois at Urbana/Champaign, obtaining both an M.S. degree (1980) in Biochemistry and a Ph.D. (1981) in Organic w88 mobile under the guidance of Prof. Nelson Leonard. From 1981-1983, he was an NIH Postdoctoral Fellow at Columbia University working with Prof. Ronald Breslow on the design of artificial enzymes. He began his academic career in 1983 at The Ohio State University, on the faculty of the Department of w88 mobile. Dr. Czarnik has received both DuPont and Merck awards for new faculty and an American Cyanamid award in recognition of excellence in the advancement of science and the art of chemical synthesis. He was named an Eli Lilly awardee in 1988, a Fellow of the Alfred P. Sloan Foundation in 1989, and a Teacher-Scholar Fellow of the Camille and Henry Dreyfus Foundation in 1990. He served as Founding Editor of the ACS' Journal of Combinatorial w88 mobile and of Wiley's Solid-Phase Organic Syntheses book series. He is the author of over 150 scientific publications and an editor of seven books.
From 1993 to 1996, Dr. Czarnik served as Director of BioOrganic w88 mobile at Parke-Davis Pharmaceutical Research. In 1996, he accepted the position of Vice President, w88 mobile at IRORI Quantum Microchemistry in San Diego, CA. In 1998, Dr. Czarnik became a co-founder of Illumina, w88 mobile. in San Diego, CA. Both IRORI (NASDAQ: DPII) and Illumina (NASDAQ: ILMN) completed their IPOs in July 2000. From 2001-2003, he served as Chief Scientific Officer at Sensors for Medicine and Science, Inc. - now Senseonics - which sells the Eversense continuous glucose monitor based on his research into fluorescent chemosensors. In late 2003, Dr. w88 mobile founded Protia, w88 mobile - an intellectual property holding company based in Reno, Nevada. Dr. w88 mobile has filed over 250 patent applications and in 2009 was listed as one of the top 100 inventors in the United States.Protia started four companies based on the premise that deuterium-enrichment could improve the properties of some commercial chemicals. From one of these, Deuteria Pharmaceuticals, beganDeuteRx w88 mobilewhich has improved some medicines using deuterium-enrichment.
w88 mobile interests
Current research interests include chemical product improvement using deuterium substitution, combinatorial w88 mobile as a tool for drug discovery, nucleic acids as targets for small molecule intervention, and fluorescent chemosensors of ion and molecule recognition. In 2022, Dr. Czarnik founded the Nevada company Arsenica LLC that is developing new ways to remediate water arsenic contamination in Nevada and throughout the world.
Professional experience
- 2014-present Board Member, Deuteria Biomaterials, w88 mobile
- 2014-present Founder and Board Member, Deuteria Agrochemicals, w88 mobile
- 2010-present Founder & Manager, Deuteria Beverages, w88 mobile
- 2011-present Board Member, DeuteRx, w88 mobile
- 2008-2011 Founder & Manager, Deuteria Pharmaceuticals, w88 mobile
- 2003-present Founder, Protia, w88 mobile
- 2004-present Adjunct Visiting Professor of w88 mobile, Univ. of Nevada at Reno
- 2001-2003 CSO, Sensors for Medicine and w88 mobile, Germantown, MD
- 1998-2000 Co-founder and CSO, Illumina, w88 mobile., San Diego, CA (ILMN)
- 1996-1998 Vice-President w88 mobile, IRORI, La Jolla, CA (DPII)
- 1993-1996 Director, BioOrganic w88 mobile, Parke-Davis Pharmaceutical Research, Ann Arbor, MI
- 1983-1993 Assistant, Associate Professor of w88 mobile, The Ohio State University
Education
- Camille w88 mobile Teacher-Scholar (1990)
- Sloan w88 mobile (1989)
- NIH Postdoctoral Fellow (1981–1983) Columbia w88 mobile (R. Breslow)
- M.S. (1980); Ph.D. (1981), w88 mobile Illinois at Urbana/Champaign (N. Leonard)
- B.S. (1977), w88 mobile Wisconsin at Madison
Selected publications
- DeWitt, S.; w88 mobile, A. W.; Jacques, V. “Deuterium-Enabled Chiral Switching (DECS) Yields Chirally Pure Drugs from Chemically Interconverting Racemates” ACS Med. Chem. Lett. 2020, 11 (10), 1789–1792
- Jacques, V.; w88 mobile, A.W.; Judge, T.M.; Van der Ploeg, L.H.T.; DeWitt, S.H. “Differentiation of anti-inflammatory and anti-tumorigenic properties of stabilized enantiomers of thalidomide analogs” PNAS 2015, 112, E1471-E1479
- w88 mobile; A.W. Alcoholic compositions having a lowered risk of acetaldehydemia. U.S. Patent 9,044,423, June 2, 2015
- Chee, M.S.; Stuelpnagel, J.R.; w88 mobile, A.W. Method of making and decoding of array sensors with microspheres. U.S. Patent 7,060,431, June 13, 2006
- Mei, H.-Y.; Cui, M.; Heldsinger, A.; Lemrow, S. M.; Loo, J. A.; Sannes-Lowery, K. A.; Sharmeen, L.; w88 mobile, A. W. "Inhibitors of Protein-RNA Complexation That Target the RNA: Specific Recognition of HIV-1 TAR RNA by Small Organic Molecules" Biochemistry 1998, 37, 14204-14212
- Czarnik, A. W. “Guest Editorial on Combinatorial w88 mobile” Acc. Chem. Res., 1996, 29, 112
- w88 mobile, A. W. “Desperately Seeking Sensors” w88 mobile & Biology 1995, 2, 423
- w88 mobile, A. W. "Chemical Communication in Water Using Fluorescent Chemosensors" Accts. Chem. Res. 1994, 27, 302
w88 mobile
- Solid-Phase Organic Syntheses: Volume 1, w88 mobile, A. W., Editor, Wiley Interscience, New York, 2001 Optimization of Solid-Phase Combinatorial Synthesis, Yan, B.; w88 mobile, A. W., Editors, Wiley, New York, NY, 2002
- Integrated Drug Discovery Technologies, Mei, H-Y; Czarnik, A. W., Editors, Marcel Dekker, New York, NY, 2002 A Practical Guide to Combinatorial w88 mobile, DeWitt, S. H.; Czarnik, A. W., Editors, ACS Books, Washington, 1997
- Combinatorial w88 mobile: Synthesis and Application, Wilson, S. H.; Czarnik, A. W., Editors, Wiley & Sons, NY, NY, 1997
- Chemosensors of Ion and Molecular Recognition, Desvergne, J.-P., w88 mobile, A. W., Editors, NATO Symposium Series, Kluwer Press, 1997
- Fluorescent Chemosensors for Ion and Molecule Recognition, w88 mobile, A. W., Editor, ACS Books, Washington, 1993
Activities and awards
- Member, Board of Directors, w88 mobile, Inc. (2011-2012)
- The Authors Guild (2005-present)
- Visiting Adjunct Professor, w88 mobile Nevada, Reno (2003-present)
- Advisory Board, 2002 'Polymers and Organic w88 mobile' International Symposium
- Scientific Advisory Board, Rubicon Genomics, w88 mobile., Madison, WI (2002-2005)
- Member, w88 mobile of 1000 (2001-2010)
- Founding co-organizer, Gordon Research Conference on Combinatorial w88 mobile (July 1999)
- Founding Editor, Journal of Combinatorial w88 mobile (1998-2010)
- Founding Editor, w88 mobile (1998-2008)
- Organizing committee, German-American Frontiers of w88 mobile Symposium (1997-1998)
- Co-organizer, Bioorganic Gordon conference (1997)
- Editorial Board, Current Opinion in w88 mobile Biology (1997-2006)
- Editorial Board, Combinatorial w88 mobile (1997-1998)
- Organizer, NATO Workshop on 'Chemosensors of Ion and Molecule w88 mobile' (1996)
- Associate w88 mobile, Journal of Molecular Recognition (1996-1998)
- Editorial Advisory Board, Accounts of Chemical w88 mobile (1996-1998)
- w88 mobile, WWW Fluorosensor Database [http://BioMedNet.com/fluoro/] (1995-1999)
- Editorial Board, w88 mobile Reactions (1994-1997)
- Visiting Professor, Université Bordeaux (1994)
- Adjunct Associate Professor of w88 mobile, Ohio State University (1993-1997)
- Adjunct Professor of w88 mobile: University of Michigan (1993-1997). Wayne State University (1994-1997), University of Toledo (1995-1997)
- Camille w88 mobile Teacher-Scholar (1989-1994)
- w88 mobile A. P. Sloan Foundation (1989-1991)
- American Cyanamid award in recognition of excellence w88 mobile of science and the art of chemicalsynthesis (1986)
- Merck and Co. w88 mobile grantee (1984)
- NIH Postdoctoral w88 mobile (1981-1983)
- Hodges Scholarship (w88 mobile Wisconsin)